According to the Metropolitan Life Insurance Co., there were 35 catastrophes—causing over 100 deaths each—in the US during 1941–75. The two greatest disasters were the Texas City fire and explosion in 1947 which took 561 lives, and the fire in a Boston nightclub in 1942, which caused 492 deaths. More than half of the major US disasters resulted from natural catastrophes of various kinds.
Since 1975, there was Colorado’s Big Thompson River Canyon flash flood on July 31, 1976, when 145 persons perished.
“For then there will be great tribulation, such as has not been since the beginning of the world until this time, no, nor ever shall be.” – Matthew 24:21